When a thousand activists storm a Wisconsin beagle research facility, college dropout Jake Morrison gets doused in an experimental serum — and wakes up with a PRIMAL SYSTEM in his vision and canine superpowers in his blood. As the viral Therian trend explodes from Argentina to Los Angeles and a humanoid robot runs a half-marathon in Beijing, Jake discovers the serum is just phase one of a corporate conspiracy involving weapon-grade narcotics, illegal genetic experiments, and an army of real animal-hybrids. The System says survive. Jake says dominate.